In residency and med school we are always taught the indications for emergent CRRT as the mnemonic: AEIOU Acidosismetabolic acidosis with a pH < 7.1 Electrolytes hyperkalemia > 6.5 mEq/L refractory to treatment or rapidly rising levels in potassiumIngestionswith dialyzable drug, including salicylates, lithium, isopropanol, methanol, and ethylene glycol (SLIME)Overloadvolume overload that does not respond …
Only the A-E-I-O-U’s to start RRT and now we know “Y”! The Start-AKI Trial
I CAN Drive 65?…In Shock: A Trial of MAP 60-65 in Patients 65 years or older requiring vasopressors
Atrial fibrillation in the ICU: Tough AF to Treat, Sick AF to care for…
Peer Reviewed by Dr. Sagar Dave, DO Every once in a while, it’s a good thing to get down to the nitty gritty of things. I think this is most helpful in common situations. Atrial fibrillation is one of those things to have quickly accessible in your internal brain. In this episode I want to …
Conservative vs Interventional Management of Spontaneous Primary Pneumothoracies (PSP)
COVID-19 RISK FACTORS: Who gets them and why. You are going to ACE this one…
Now usually I don’t go and make wild conjectures and hypotheses. But Im going to discuss a pretty interesting (wild conjecture?) one that on paper seems to make sense to me. Let’s look at the COVID-19 risk factors for who gets severe disease and put them in a molecular and biological framework. If you want you …
What No COVID? Then at Least Lets Talk Steroids- in ARDS that is…
Reference: Villar. Dexamethasone treatment for the acute respiratory distress syndrome: a multicentre, randomised controlled trial. Lancet Respir Med 2020; 8: 267–76. I know what you are thinking, “What gives? No COVID!” Well the two of you who read this are probably inundated with COVID info. So to give our brains a change I thought I would …
Permissive Hypotension and Shock
ESETT: A Randomized Trial of 3 AEDs for Status Epilepticus
Kapur, J et al. Randomized Trial of Three Anticonvulsants Medications for Status Epilepticus. NEJM 2019;381;2103-13 This was a randomized, double-blinded, national multicenter pragmatic study to determine comparative effectiveness of traditional anti-epileptic medications in status epilepticus. The purpose of this study is to see if there is a difference between levetiracetem (Keppra), fosphenytoin (Cerebyx), and valproate (Depakote) in treatment of …
We’re Back Baby!! The Quick hit article: For ESBL, Just Say NO to PIP/TAZO
Effect of Piperacillin-Tazobactam vs Meropenem on 30-Day Mortality for Patients With E coli or Klebsiella pneumoniae Bloodstream Infection and Ceftriaxone Resistance A Randomized Clinical Trial This was a randomized, double-blinded, international multicenter pragmatic (phew! That’s a mouthful!) study to determine if piperacillin/tazobactam (pip-taz) is non-inferior to meropenem. The reason for this study is to see if …